From ... in Health — Nov 19, 2024

DMSO has been proven to protect and heal the heart, lungs, liver, kidneys and prostate, and treat infertility

The therapeutic actions of DMSO, or dimethyl sulphoxide, make it well-suited to treat challenging conditions throughout the body, including many internal organs, such as the heart, liver, lungs, pancreas, kidneys and others.

DMSO has been proven to treat various diseases and conditions, including heart attacks, liver cirrhosis, gallstones, ARDS, lung damage from inhaling smoke, pulmonary fibrosis, pancreatitis, diabetes, nephritis, kidney stones, polycystic kidney disease, cystitis, epididymitis, genital pain, prostatitis, urethral syndrome, enlarged prostates, tubal infertility, endometrial inflammation and fibrosis.

In the article ‘How DMSO Protects and Heals the Internal Organs‘, A Midwestern Doctor (“AMD”) reviewed DMSO treatment protocols for conditions of our internal organs and provided general DMSO information for those looking to use it for their own health.

The following is a summary of AMD’s article on protecting and healing our internal organs. We encourage our readers to want to know more to refer to AMD’s article as in the summarising of it, details will get lost in translation.

In a summary of another article in AMD’s DSMO series we previously published on strokes and neurological damage, we attached a PDF copy of AMD’s article because it is easier to search for specific terms in a PDF file. We have done the same with this article, see the PDF below.

For those who are interested, we have also published a summary of the book ‘Healing with DMSO’ by Amandha Vollmer. You can read our book summary HERE.

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How DMSO Protects and Heals the Internal Organs

Table of Contents

Strokes, Injuries, and Autoimmune Disorders

DMSO has been shown to effectively treat strokes, traumatic brain injuries, spinal cord injuries and many circulatory disorders, as well as cure a variety of autoimmune and connective tissue disorders.

AMD has received numerous reports from people who have experienced remarkable effects from using DMSO, which are similar to those reported in the 1960s before the FDA’s opposition. Despite its effectiveness, DMSO faced opposition from the FDA and the pharmaceutical industry, which led to its decline in popularity, but thousands of studies have confirmed its value in treating various conditions.

AMD has compiled studies on DMSO’s effects on internal organs, including animal studies that used research protocols to induce common diseases and then test DMSO’s ability to prevent them. These studies often involved inducing ischemia-reperfusion injuries by clamping an artery that feeds an organ and then unclamping it, and then testing DMSO’s ability to prevent or treat the resulting damage.

Note: Reperfusion is the restoration of blood flow to an organ or tissue after a period of ischemia (reduced blood flow).

Regenerative Properties and Mechanism of Action

DMSO has various benefits for the body, including reducing autoimmunity, increasing blood circulation and healing injured tissues, and it plays a crucial role in understanding a specific disease process that underlies many illnesses.

This disease process is characterised by the progression of tissue damage due to stressors, with more potent stressors causing faster progression and weaker stressors causing slower progression.

The further the tissue damage progresses, the harder it is to reverse, but with the correct therapy, it can almost always be done, and many regenerative therapies work by getting “shocked” cells to come back to life and start working again.

DMSO can reverse this process, particularly in rapidly progressing instances caused by significant stressors, such as strokes or severe injuries, and it is more effective when given shortly after the stressor.

For slower and more chronic versions of this process, a systemic regenerative therapy is typically needed.

Heart Conditions

DMSO has been found to protect the heart from permanent ischemia-reperfusion injuries, such as heart attacks, by reducing tissue necrosis and left ventricular dysfunction, and increasing cardiac output.

Studies have shown that DMSO can reduce heart damage when given before or after a heart attack, and it can also reduce damage caused by ischemic hearts being reperfused with a calcium ion-containing solution.

DMSO has been found to prevent ischemia-reperfusion injuries from causing severe contractures in heart cells and the formation of contraction bands, and it may also prevent the t-tubules within heart cells from sealing and remodelling after a shock or stressful conditions.

Additionally, DMSO has been found to prevent heart damage caused by isoproterenol, which can cause damage similar to that seen after a heart attack. It has been found to have protective effects on the heart, including reducing myocardial fibre necrosis, preventing ventricular aneurysms and cardiac rupture, and minimising residual myocardial fibrosis in rats given isoproterenol.

DMSO can cause stem cells to differentiate into heart cells, particularly when used in conjunction with another medication, which is a key component of regenerative medicine.

Low concentrations of DMSO (less than 0.5%) have been shown to enhance the respiratory control ratio and cellular viability of heart cells, while higher concentrations (3.7%) can be harmful.

DMSO has been found to prevent heart damage caused by dietary copper deficiency.

DMSO can increase or decrease the force of heart contractions, depending on the concentration used, and does not alter cardiac rhythm.

Gastrointestinal Issues

In the gastrointestinal tract, DMSO has been used to heal irritation, inflammation and bleeding, with studies showing its effectiveness in treating conditions such as irritable bowel syndrome, gastritis, peptic ulcers, enterocolitis and mucomembranous colitis.

A double-blind, randomised study found that DMSO was more effective than standard therapies in treating recurrent attacks of proctosigmoidal ulcerative colitis, with 84% of patients recovering compared to 51% on standard treatment.

DMSO has been shown to reduce the risk of stress-induced gastric ulcers in hospitalised patients with pelvic fractures or hypovolemic shock, with only 4% of patients developing an ulcer compared to 22% in the control group.

Studies have also found that DMSO can reduce the recurrence of duodenal ulcers, with one study showing a recurrence rate of 13% in patients taking DMSO compared to 65% in those taking a placebo.

Another study found that DMSO was more effective than cimetidine in treating duodenal ulcers that did not heal despite 3 months of treatment, with 100% of patients recovering compared to 60% on cimetidine alone.

A randomised double-blind study found that DMSO was effective in treating symptomatic acute duodenal ulceration, with all patients recovering after 8 weeks of treatment.

A study comparing the effectiveness of cimetidine, DMSO, and allopurinol found that 67% of patients who received cimetidine relapsed, while only 6% of those who took DMSO and 5% of those who took allopurinol relapsed.

A randomised study of 101 patients with hematemesis due to erosive gastritis found that those who received oral allopurinol and DMSO had a significantly lower rate of further episodes of hematemesis (8%) compared to the control group (29%) and fewer required subsequent surgery. A subsequent endoscopy showed evidence of haemorrhagic inflammation in 44% of the control group and 9% of those who received DMSO and allopurinol.

A doctor reported on five patients with recurrent duodenal ulcers who were given DMSO and found that all five had no recurrence of ulcer symptoms after a year, and also experienced improved overall health.

A 55-year-old woman with severe digestive tract issues, including internal bleeding and anaemia, was treated with injected DMSO and B-12 after other treatments failed, and recovered, with no subsequent blood transfusions required over six years of follow-up.

A study on rats found that intravenous DMSO administered after cutting off the blood supply to the small intestine prevented gangrene and ischemic damage to the intestines in 28 out of 29 cases.

Liver, Gallbladder, and Biliary System Issues

Research has also explored the effects of DMSO on the liver, gallbladder and biliary system, including its ability to reduce ischemia-reperfusion injuries to the liver, prevent dimethylnitrosamine-induced liver damage, inhibit liver necrosis and oxidative stress, and prevent liver damage caused by toxic substances such as halothane, chloroform and bromobenzene.

DMSO has been found to protect the kidneys from chloroform-induced toxicity, with a follow-up study showing that administering DMSO 24 hours after exposure reduced liver damage four-fold and ALT levels eight to 16-fold.

A study on 12 patients with terminal liver cirrhosis who stopped drinking alcohol and took daily oral DMSO and aloe vera showed significant improvements in health, reduced vomiting and improved liver function tests, with all eight patients who continued the program for six months showing better condition than at the start of the study.

DMSO has been found to mitigate the effects of obstructive jaundice in rats, and a Japanese study found that injecting 90% DMSO mixed with 5% hexametaphosphate into the biliary tract effectively dissolved gallstones within the liver and was safe for patients.

A study on mice found that injecting 50% DMSO directly into the biliary tree caused no irritation, but 65% DMSO caused transient irritation, suggesting that DMSO is safe to administer to the biliary tract in lower concentrations.

DMSO for Lung Conditions

DMSO has been found to protect the lungs from various injuries, including ischemia-reperfusion injuries, haemorrhagic shock, and toxin-induced damage, and has also been shown to prevent acute pulmonary oedema and oxygen deprivation.

Studies have found that DMSO can prevent significant inflammation and tissue injury following traumatic impact to the lung, and nebulised DMSO has been found to reduce lung damage in sheep that inhaled smoke.

However, a rabbit study found that chronically nebulising DMSO caused pathologic changes in the liver and lungs, leading to the advice against chronic nebulisation of DMSO, with the recommendation to only use it for acute lung injuries.

DMSO has shown potential in treating Acute Respiratory Distress Syndrome (“ARDS”), a severe lung condition that often requires ventilation, by reducing inflammation and fluid in the lungs.

Studies in hamsters and mice have demonstrated DMSO’s ability to reduce lung inflammation and fluid leak, as well as damage to the lining of the lungs, when administered after inducing ARDS with inflammatory peptides or bacterial LPS.

Note: Lipopolysaccharide (“LPS”) is a potent inflammatory agent that can cause severe lung damage, leading to ARDS and chronic lung disease.

A human study found that intravenous DMSO administration at concentrations under 10% produced a dramatic improvement in all three patients with ARDS, with one patient’s lungs returning to normal after a week, and another patient showing improvement within an hour when DMSO was nebulised.

However, another study suggests that DMSO should not be used alone to treat bacterial pneumonia, as it can reduce immune cell infiltration, which can be beneficial but also problematic in fighting off infections.

DMSO has also been found to be beneficial in treating chronic lung diseases, such as chronic pulmonary fibrosis, and can increase the potency of antibiotics when used in combination.

In older patients with chronic respiratory insufficiency, daily intramuscular DMSO administration was found to bring about a recovery in 81% of patients without the need for hospitalisation.

Additionally, DMSO has been shown to be effective in treating asthma.

Diabetes and Pancreatitis

DMSO has also shown promise in treating diabetes and pancreatitis, with some Type 1 and Type 2 diabetics reporting a reduction in their need for insulin and alleviation of pain from diabetic peripheral neuropathy.

Studies have found that DMSO can protect the insulin-producing cells of the pancreas from damage, prevent autoimmune recurrence of Type 1 diabetes, and increase the production of insulin by 2-2.5 times when combined with the hormone GLP-1.

A 1977 study found that DMSO injection prior to administering alloxan, a toxic substance that can induce diabetes, prevented the development of diabetes in some cases.

A mouse study found that DMSO protected transplanted insulin-secreting cells from immune system attack, decreasing the expression of certain immune cells and increasing Treg cell differentiation, which can help prevent spontaneous diabetes and autoimmune recurrence of Type 1 diabetes.

The study’s findings suggest that DMSO could help treat diabetes by enhancing glucose-induced and tolbutamide-stimulated insulin secretion, potentially allowing GLP-1 users to use a lower dose of the medication.

However, another study found that high doses of DMSO can inhibit insulin secretion, although this dose is much higher than what a DMSO user’s pancreas would typically be exposed to.

DMSO has been shown to be effective in treating pancreatitis, a condition with limited conventional treatment options, by improving pancreatic microcirculation, reducing ICAM-1 expression, and subsequent leukocyte adhesion.

Studies on rats and mice have demonstrated that DMSO can reduce pancreatic oedema, protect the pancreas from cerulein-induced pancreatitis and inhibit lipid peroxidation in pancreatic tissue.

A randomised double-blind trial found that rectal administration of 10% DMSO significantly reduced pain in patients with chronic recurring pancreatitis, with 57% of patients pain-free after 12 hours and all patients pain-free after 24 hours.

Kidney Conditions

Research on the kidneys has shown that DMSO can be safely used without causing significant toxicity, with studies on rabbits, paraplegics and dogs demonstrating no adverse effects on urinary function or kidney damage.

However, high concentrations of DMSO (above 2.1M) can produce toxic effects on the kidneys, and IV administration of DMSO can cause a transient increase in blood cells if the concentration is too high.

DMSO has been found to have a diuretic effect, which can be beneficial in certain situations, such as reducing excessive fluid in regions where it has leaked.

A rat study demonstrated that DMSO can protect against ischemia-reperfusion injuries in the kidneys, with all DMSO-treated rats surviving and having near-normal kidney function after renal ischemia was induced.

DMSO has been found to protect and preserve kidney function in various studies involving animals, including dogs, rats, and mice, by preventing ischemia-reperfusion injuries, toxic and dietary injuries, and radiation-induced damage.

In a study involving dogs, DMSO preserved near-normal kidney function, whereas saline-treated dogs experienced significant renal failure, with one death and four cases of transient renal failure.

A rat study using nuclear magnetic resonance imaging found that DMSO protected the kidneys from damage caused by oxygen deprivation, but did not prevent the transient drop in kidney function during this period.

DMSO has been shown to prevent kidney damage caused by mercury, gentamycin, and radiation, and to restore levels of GSH and SOD enzyme activity to near normal.

In rats with dietary copper deficiencies, DMSO attenuated the increase in blood urea nitrogen and significantly decreased gamma glutamyl transferase caused by the copper deficiency.

DMSO has been found to improve renal function in patients with amyloidosis, with studies and case reports showing improvements in kidney function in patients with amyloid A amyloidosis and renal amyloidosis.

DMSO has been found to inhibit the kidney’s Na+-K+-ATPase pump, similar to Ouabain or atrial natriuretic peptides, but through a different mechanism.

A study of 56 DMSO-treated rats with lupus nephritis found that those who received DMSO had nearly normal kidneys, whereas the controls had significant damage to their kidneys.

DMSO has been found to resolve kidney stones in patients, with a study of six patients finding that intravenous DMSO resolved the condition in 2-3 treatments, and a rat study finding that DMSO reduced the incidence of kidney stones in rats fed a diet designed to create kidney stones.

Exposing kidney cells to 10-20% DMSO increased their metabolism, while higher concentrations were found to be toxic to the kidneys.

DMSO has been found to reduce protein leaking into the urine in rat studies of Heymann nephritis and lupus nephritis, suggesting it prevents autoimmune kidney damage.

Genitourinary Disorders

DMSO has been found to be effective in treating various genitourinary disorders, including inflammation of the bladder, particularly interstitial cystitis, also known as painful bladder syndrome.

A 1967 study showed that DMSO administration, either orally or directly into the bladder with a catheter, can help with interstitial cystitis, as well as other inflammatory conditions of the urinary tract.

The study found that 50% of patients with radiation cystitis had a positive response to DMSO treatment, with 3 having an “excellent” response, 2 “good,” and 1 “fair.”

Additionally, 75% of patients with chronic prostatitis benefited significantly from DMSO treatment, with 12 having an “excellent” response, 14 “good,” and 90% showing improvement in inflammation of the prostatic urethra.

Another study found that 3 out of 4 men with chronic excessive urination due to various conditions, including chronic prostatitis and interstitial cystitis, had an excellent response to DMSO treatment.

A Polish study also found that DMSO can help with urethral syndrome, a condition characterised by chronic irritation of the urethra without signs of infection.

There are many anecdotal reports of DMSO being helpful for various urinary tract conditions, including Peyronie’s disease, an unfortunate contractile condition that causes a gradual curvature of the penis and significant pain during intercourse.

Dr. Stanley Jacob, a pioneer of DMSO, recommended its use for enlarged prostates that were making it difficult to urinate, and Dr. Pierre Kory shared a case of DMSO curing a patient’s prostatitis.

A physician with extensive experience using DMSO reported that 40 out of 40 patients with confirmed bacterial prostatitis eliminated the bacteria in their prostate with a single dose of antibiotic dissolved in DMSO administered via catheter three times a week for 4 weeks, with no recurrences.

DMSO has also been found to be safe, with no organ damage noted in a patient who received 50 grams of DMSO intravenously daily for five months.

Dr. Stanley Jacob, a pioneer of DMSO, recommended its use for enlarged prostates that were making it difficult to urinate, and Pierre Kory shared a case of DMSO curing a patient’s prostatitis.

Reproductive Tract Issues

Research has shown that DMSO can help protect and heal the ovaries and uterus, with studies indicating its potential in treating reproductive tract issues.

A rat study found that DMSO combined with erythropoietin protected the ovaries from ischemia-reperfusion injuries, suggesting its potential to prevent ovarian damage.

A 1975 Chilean study used DMSO to treat infertile women with obstructed fallopian tubes, resulting in 57.4% of the 47 patients analysed becoming pregnant, with 12 successful deliveries and 7 normal pregnancies at the time of publication.

The study involved injecting a DMSO mixture into the fallopian tubes via ascendant hydrotubation, with a series of 6 treatments given every 3 days, followed by temporary breaks and evaluation to determine if the tubes had opened.

The treatment had a relatively low risk of side effects, with only 1.5% of intubations resulting in discomfort, fatigue or psychiatric changes, which did not require suspending treatment.

Horse studies have shown that applying DMSO directly into the uterus does not harm its lining, and may even improve its function and structure, particularly in cases where the uterus has been damaged by freezing.

One study found that administering 10-30% DMSO into the uteruses of infertile horses resulted in significant improvement to the uterine lining in 18 out of 27 horses, with signs of improved fertility, although the trial’s design made it impossible to confirm this improvement.

The use of DMSO in treating reproductive tract issues represents a new therapeutic principle, as discovered by Dr. Stanley Jacob, which has the potential to address challenges that remain unresolved in modern medicine.

DMSO’s ability to protect and heal the ovaries and uterus makes it a promising treatment option for various gynaecological conditions, although further research is needed to fully explore its potential.

Future of DMSO and Conclusion

The use of DMSO is proposed as a mainstay therapy for preventing organ failure due to poisoning, such as a drug overdose, and for improving outcomes in challenging diseases requiring hospital or intensive care admission.

AMD believes that a paradigm shift in the acceptance of DMSO as a treatment option is imminent due to several factors, including the loss of public and medical faith in traditional medical orthodoxy.

The widespread use of social media platforms like Twitter (now called X) has enabled the rapid dissemination of information, making it difficult to censor medical truths and contributing to the potential paradigm shift.

The incoming administration, particularly Robert F. Kennedy Jr., is committed to addressing this issue, and AMD aims to support this shift by providing information and protocols for using DMSO.

In the final part of the article, AMD discussed the use of DMSO in treating the various conditions mentioned in the article, including cirrhosis, prostate enlargement, GI ulcers, ulcerative colitis, ARDS, heart attacks, gallstones, gastric bleeds and smoke inhalation. Additionally, AMD provided revised instructions for sourcing and using DMSO safely, incorporating feedback received about his articles over the past few weeks. The Protocols detailed in the final part of AMD’s article are behind a paywall so we have not included them here.

Articles in A Midwestern Doctor’s DSMO Series So Far

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References:

Search Results

Bookmarks

DMSO has been proven to protect and heal the heart, lungs, liver, kidneys and prostate, and treat infertility

Strokes, Injuries, and Autoimmune Disorders

Regenerative Properties and Mechanism of Action

Heart Conditions

Gastrointestinal Issues

Liver, Gallbladder, and Biliary System Issues

DMSO for Lung Conditions

Diabetes and Pancreatitis

Kidney Conditions

Genitourinary Disorders

Reproductive Tract Issues

Future of DMSO and Conclusion

Articles in A Midwestern Doctor’s DSMO Series So Far

Search Results

Bookmarks

Strokes, Injuries, and Autoimmune Disorders

Regenerative Properties and Mechanism of Action

Heart Conditions

Gastrointestinal Issues

Liver, Gallbladder, and Biliary System Issues

DMSO for Lung Conditions

Diabetes and Pancreatitis

Kidney Conditions

Genitourinary Disorders

Reproductive Tract Issues

Future of DMSO and Conclusion

Articles in A Midwestern Doctor’s DSMO Series So Far

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