mRNA covid vaccination during early pregnancy is linked to a significantly higher number of foetal losses, a new study finds
A new preprint investigated the association between mRNA covid injections (almost all Pfizer) and foetal loss rates in early pregnancy in Israel. The study found that covid vaccination during gestational weeks 8-13 is associated with highe
A new preprint investigated the association between mRNA covid injections (almost all Pfizer) and foetal loss rates in early pregnancy in Israel. The study found that covid vaccination during gestational weeks 8-13 is associated with higher-than-expected foetal losses, including spontaneous abortions, induced abortions and stillbirths.
There were approximately 3.9 additional foetal losses per 100 pregnancies after dose 1 and 1.9 additional losses after dose 3.
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Josh Guetzkow, Retsef Levi et al. Hammer Home Risks of Covid-19 Injections to Pregnant Women, Particularly in Gestational Weeks 8-13
By Jessica Rose
A new preprint was uploaded on 20 June 2025 to the medRXiv preprint server entitled: ‘Observed-to-Expected Foetal Losses Following mRNA Covid-19 Vaccination in Early Pregnancy’.1 Among the authors are my friends and colleagues Josh Guetzkow and Retsef Levi – we have all been saying this for years.
The study investigates the association between mRNA covid-19 injection (primarily Pfizer products) during early pregnancy and foetal loss rates in Israel. As if we don’t have enough to worry about. (It is important to remember that pregnant women were excluded from the initial covid-19 injection clinical trials.)
The study addresses the limited safety data for injection in early pregnancy, particularly gestational weeks 8-13, when teratogenicity risks are highest.
As they point out in the preprint, existing observational studies face methodological challenges, such as healthy vaccinee bias, so the authors used an observed-to-expected foetal loss analysis. This means that they statistically determined whether the number of foetal losses (including spontaneous abortions, induced abortions and stillbirths) in a specific group – such as pregnant women injected with mRNA covid-19 injectable products during early pregnancy – differed from what would be expected based on historical data.
They used data from Israeli Maccabi Healthcare Services (“MHS”), covering 226,395 pregnancies from 2016 to 2022 to assess whether injection (with Pfizer’s BNT162b2 injectable product) was linked to higher-than-expected foetal losses. It was.
They analysed pregnancies in women where their last menstrual periods were between 1 March 2016 and 28 February 2022, using MHS’s electronic health record database, and compared observed foetal losses to expected losses in cohorts injected with covid-19 injectable product doses 1 or 3 during the gestational weeks 8-13 and 14-27.
Lo and behold, they actually had a control group that included women vaccinated for influenza during the same gestational periods or injected for covid-19 or influenza before pregnancy.
Expected foetal loss rates were derived from a logistic regression model trained on data spanning 2016-2018, adjusting for individual risk factors like maternal age, co-morbidities and socioeconomic status. The analysis excluded pregnancies that occurred before week 8, due to inconsistent documentation, and focused on late foetal losses (after weeks 14, 20 and 25) to address potential biases from elective abortions.
What They Found
It is provably clear: Covid-19 injection during gestational weeks 8-13 is associated with higher-than-expected foetal losses. Colour me shocked.
For dose 1, there were approximately 3.85 additional foetal losses per 100 pregnancies (95% CI: 2.55-5.14), and for dose 3, 1.90 additional losses (95% CI: 0.39-3.42), with most excess losses occurring after week 20. That is significant.
In contrast, injection during weeks 14-27 showed lower-than-expected foetal losses. Influenza vaccination during weeks 8-27 consistently resulted in fewer foetal losses than expected, which is likely due to healthy vaccinee bias.
N.B. In case you don’t know, the healthy vaccinee bias is when healthier people get vaccinated, making vaccines seem safer in studies because these people already have better health outcomes.
Women injected in the context of covid-19 or influenza before pregnancy had foetal loss rates at or below expected levels. Late foetal loss analysis confirmed persistent excess losses for covid-19 injection in weeks 8-13, with 1.66 and 0.95 additional losses per 100 pregnancies for doses 1 and 3, respectively, by week 25.
They indeed conducted study robustness checks, including re-estimating the baseline model with data from 2016–2019 and adjusting the follow-up start to week 10, which yielded consistent results. Influenza vaccination cohorts from 2018-2019 also showed lower-than-expected foetal losses, supporting the model’s reliability. Comparisons of covariate distributions between covid-19 and influenza vaccination cohorts revealed slight differences, which were adjusted for in the analysis. The study also examined SARS-CoV-2 infections, finding no significant increase in foetal losses, though unvaccinated women infected in weeks 8-13 had slightly higher-than-expected losses. This is explained by the notorious spike protein, in my opinion.
The authors concluded that mRNA covid-19 injection during the gestational weeks 8-13 is associated with a significantly higher-than-expected number of foetal losses, particularly after week 20, highlighting safety concerns in early pregnancy. The lower-than-expected losses for influenza vaccination also highlight the influence of healthy vaccinee bias, which importantly, may mask risks in other studies.
The trolls will shout “preprint,” of course, but this study is very hard to refute, especially in the context of anomalously large signals in multiple pharmacovigilance databases worldwide. Anyone who does peer review this study will not have many issues with the analysis, as it is sound.
Additional reading:
- 31% of women who were exposed to covid-19 products before pregnancy experienced a miscarriage according to VAERS domestic data, Jessica Rose, 12 November 2023
- According to CDC, ‘people’ can get pregnant and should be injected with covid shots, Jessica Rose, 12 November 2023
- “To Evaluate the Safety, Tolerability, and Immunogenicity of BNT162b2 Against Covid-19 in Healthy Pregnant Women 18 Years of Age and Older”, Jessica Rose, 20 August 2023
- ‘Exposure’ during pregnancy…, Jessica Rose, 13 December 2022
Note:
1 Josh Guetzkow, Tal Patalon, Sivan Gazit, Tracy Beth Hoeg, Joseph Fraiman, Yaakov Segal, Retsef Levi. Observed-to-Expected Foetal Losses Following mRNA COVID-19 Vaccination in Early Pregnancy. medRxiv 2025.06.18.25329352; doi: https://doi.org/10.1101/2025.06.18.25329352
About the Author
Dr. Jessica Rose is a Canadian researcher with a Post Doctorate in both Biochemistry and Molecular Biology, a PhD in Computational Biology and a Master’s in Immunology, as well as a Bachelor’s Degree in Applied Mathematics. She publishes articles on a Substack page titled ‘Unacceptable Jessica’ which you can subscribe to and follow HERE. You can also follow her on Twitter (now X) HERE.
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