From ... in Biology — Feb 8, 2022

No One Can Tolerate Permanent Fever, High Antibodies

STORY AT-A-GLANCE Endless COVID-19 booster shots are being presented as the solution to the pandemic, as repeated injections increase the level of antibodies in your body.

In December 2021, for instance, Moderna reported that their COVID-19 booster shot increased the level of antibodies by 37-fold, and when a full dose was given — the same amount used for the initial shots — antibody levels rose 83-fold. Pfizer and BioNTech have also announced that their booster shots increase antibody levels, but to what end? Artificially infiated antibodies signal to your body that you're

¹²

always infected, and the resulting immune response could prove to be detrimental to your health. Such a condition can only lead to a “death zone,” accelerating the development of autoimmune conditions such as Parkinson's, Kawasaki disease and multiple sclerosis, according to tech leader and COVID analyst Marc Girardot, who urges a retreat from the vaccination “death zone” before it's too late.

Are Boosters Taking Humans to the Death Zone?

Mountaineers are familiar with the “death zone,” which describes the top portion of the world's tallest mountains — areas of such high altitude that oxygen is scarce, where humans can only survive for a matter of hours. “The same principle applies to our immune system,” Girardot explains, referring to the intense response our bodies mount in response to infection. The response includes a high fever to damage virions, T-cell elevations and increased antibody production to rid your body of “viral debris.” This is designed to be a temporary response; after the threat is neutralized, your body tamps down its immune response. Girardot states:

“Once the infection is gone, a regiment of sentinels is left in the mucus to guardthe entrance for the remainder of the epidemic, a few roaming sentinels withlifelong memory are set, and the rest wanes back down to bring peace andbalance. It's called homeostasis. The fever dissipates. T-cells self-destructrapidly. And antibodies wane progressively.”

This is by design, as a perpetual fever and high levels of antibodies keep your body in a dangerous state. Just as chronic stress — keeping your body in an extended state of “fight or fiight mode” — increases disease risks, so, too, do permanently elevated levels of antibodies. Girardot details three reasons why:

“1. Too long a fever would end up breaking down all healthy cells, and so theremedy would be worse than the illness.

³⁴⁵

2. Perpetual specialized T-cells are also dangerous as they can start off-targetattacks of healthy cells (as often occurs with immune checkpoint blockadetreatments against cancer), and would be like leaving your home filled with abattalion of armed soldiers with their guns loaded and pin-less hand-grenades.3. Finally, very high levels of antibodies with nowhere to go are also extremelydangerous. They can passively bind to receptors of healthy cells, and kickstart acascade of autoimmune diseases. Land mining where you live.”

Decreased Antibodies Isn't a Measure of Waning Immunity

Remember, your immune system is designed to work in response to exposure to an infectious agent. Your adaptive immune system, specifically, generates antibodies that are used to fight pathogens that your body has previously encountered. During normal infections, high fever and temporary T-cell elevations, along with elevated antibodies to the infection, gradually dissipate. However, declining antibodies shouldn't be confused with declining immunity. Early data on SARS-CoV-2 also found that antibody titers declined rapidly in the first months after recovery from COVID-19, leading some to speculate — incorrectly — that protective immunity against SARS-CoV-2 may also be short-lived. Senior author of the study, Ali Ellebedy, Ph.D., an associate professor of pathology & immunology at Washington University School of Medicine in St. Louis, explained, “It's normal for antibody levels to go down after acute infection, but they don't go down to zero; they plateau.” A biphasic pattern of antibody concentrations against SARS-CoV-2 was uncovered, in which high antibody concentrations were found in the acute immune response that occurred at the time of initial infection. The antibodies declined in the first months after infection, as should be expected, then leveled off to about 10% to 20% of the maximum concentration detected.

⁶⁷⁸⁹

When a new infection occurs, cells called plasmablasts provide antibodies, but when the virus is cleared, longer lasting memory B cells move in to monitor blood for signs of reinfection. Bone marrow plasma cells (BMPCs) also exist in bones, acting as “persistent and essential sources of protective antibodies.” According to Ellebedy, “A plasma cell is our life history, in terms of the pathogens we've been exposed to,” and it's in these long-lived BMPCs were immunity to SARS-CoV-2 resides. Among people who have recovered from COVID-19, most of the participants had BMPCs that secreted antibodies specific for the spike protein encoded by SARS-CoV-2 at both seven months and 11 months after infection. This is evidence of long-lasting immunity, even if levels of anti-SARS-CoV-2 spike protein (S) antibodies decline rapidly in the first four months after infection.

There's a Cost to Massive, Artificially Elevated Antibodies

COVID-19 shots are poised for a perpetual cycle of ongoing booster shots every few months. After up to two doses of the initial shot, and a third booster already on the roster, a fourth booster is already being discussed, including by Moderna CEO Stéphane Bancel, who said that the eficacy of the third shot is likely to decline over several months, necessitating another shot soon thereafter. “Many politicians and vaccine manufacturers adamantly propose repeated injections, boosters every 3 or 4 months, as if waning antibodies were a sign of lost immunity,” Girardot said. “In reality, they are scapegoating the natural drop in antibodies. It is a smokescreen to hide their failure and the ineffectiveness of these intramuscular vaccines.” The reality is, repeatedly, artificially infiating antibodies comes with a cost. It's known, for instance, that certain autoimmune diseases are seen alongside high levels of antibodies. Vaccine-induced autoimmunity is a well-known phenomenon, and molecular mimicry may be to blame.

¹⁰¹¹¹²¹³¹⁴¹⁵¹⁶¹⁷¹⁸

It occurs when similarities between different antigens confuse the immune system. There are often significant similarities between elements in the vaccine and human proteins, which can lead to immune cross-reactivity. When this occurs, researchers explained in Cellular & Molecular Immunology, “the reaction of the immune system towards the pathogenic antigens may harm the similar human proteins, essentially causing autoimmune disease.” In relation to COVID-19 shots, specifically, researchers wrote in the Journal of Autoimmunity, “Indeed, antibodies against the spike protein S1 of SARS-CoV-2 had a high afinity against some human tissue proteins. As vaccine mRNA codes the same viral protein, they can trigger autoimmune diseases in predisposed patients.” Already, case reports suggest that COVID-19 shots may trigger vaccine-induced immune-mediated and autoimmune hepatitis, and Girardot is concerned that repeated booster shots will only worsen outcomes:

“In the case of an infection, the risk is relatively limited as the bulk of antibodiesends up binding to viral material circulating in large numbers. However, in thecase of repeated doses, it's very different.After the second shot, it is likely that limited amounts of spike are produced asT-cells rapidly destroy production capacity. Thus, for most of us, largequantities of antibodies will inevitably be left idle circulating aimlessly,expanding exponentially (time x quantity) the risk of an accidental binding withcatastrophic consequences.”

Natural Infection Produces Broad Immunity

Training your body to produce singular antibodies for one spike protein cannot compare to the protection provided by natural immunity, which occurs after recovery from an illness. Speaking with Daniel Horowitz, pathologist Dr. Ryan Cole explained that natural infection produces broad immunity that can't be matched by vaccination:

¹⁹²⁰²¹²²²³²⁴

"A natural infection induces hundreds upon hundreds of antibodies against allproteins of the virus, including the envelope, the membrane, the nucleocapsid,and the spike. Dozens upon dozens of these antibodies neutralize the viruswhen encountered again.Additionally, because of the immune system exposure to these numerousproteins (epitomes), our T cells mount a robust memory, as well. Our T cells arethe 'marines' of the immune system and the first line of defense againstpathogens. T cell memory to those infected with SARSCOV1 is at 17 years andrunning still."

This may explain why a retrospective observational study published August 25, 2021, found that natural immunity is superior to immunity from COVID-19 shots, with researchers stating, “This study demonstrated that natural immunity confers longer lasting and stronger protection against infection, symptomatic disease and hospitalization caused by the Delta variant of SARS-CoV-2, compared to the BNT162b2 two-dose vaccine-induced immunity.” Pharmaceutical companies and health oficials are making plans for ongoing boosters, including combination shots that include, for example, a COVID-19 shot, a fiu shot and a respiratory syncytial virus (RSV) shot, in one injection — coming in 2023 — to avoid “compliance issues.” Nearly two dozen pathogens are currently being targeted for the development of new shots, and it's likely that you're going to see a continued push for more jabs and boosters. Will humans' immune systems, and overall health, be able to withstand such an assault? Girardot doesn't think so:

“Today, I would like to underscore the absolute lunacy of delivering theseproducts to an entire population every 3-4 months. It's nothing short of criminal.In my earnest opinion, repeated vaccine injections can only lead to oneoutcome: generalized illness and death …

²⁵²⁶²⁷²⁸²⁹

The vaccination ‘Death Zone' exists, and we need to urgently go back down inthe valley, we need to stop vaccinating, stop boosting aimless antibodies andtrust our immune systems.”

Read the full article at the original website

References:

Search Results

Bookmarks

No One Can Tolerate Permanent Fever, High Antibodies

Are Boosters Taking Humans to the Death Zone?

Decreased Antibodies Isn't a Measure of Waning Immunity

There's a Cost to Massive, Artificially Elevated Antibodies

Natural Infection Produces Broad Immunity

Search Results

Bookmarks

Are Boosters Taking Humans to the Death Zone?

Decreased Antibodies Isn't a Measure of Waning Immunity

There's a Cost to Massive, Artificially Elevated Antibodies

Natural Infection Produces Broad Immunity

Subscribe to The Article Feed