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Biology

A collection of 1139 articles

Bronchom assuages airway hyperresponsiveness in house dust mite-induced mouse model of allergic asthma and moderates goblet cell metaplasia, sub-epithelial fibrosis along with changes in Th2 cytokines and chemokines

Background: Asthma is a common obstructive airway disease with an inflammatory etiology.

Joint transcriptomic and metabolomic analysis provides new insights into drought resistance in watermelon (Citrullus lanatus)

Introduction: Watermelon is an annual vine of the family Cucurbitaceae.Watermelon plants produce a fruit that people love and have important nutritional and economic value.

Preclinical characterization of a novel investigational monoclonal antibody CM313 with potent CD38-positive cell killing activity

Introduction: CM313 is currently under clinical investigation for treatments of multiple myeloma, systemic lupus erythematosus, and immune thrombocytopenia.

Functional identification of DNA demethylase gene CaROS1 in pepper (Capsicum annuum L.) involved in salt stress

Pepper, which is a widely cultivated important vegetable, is sensitive to salt stress, and the continuous intensification of soil salinization has affected pepper production worldwide.

A case report of IgG4-related hepatic inflammatory pseudotumor in a 3-year old boy

Background: Hepatic Inflammatory Pseudotumor (IPT) is an infrequent condition often masquerading as a malignant tumor, resulting in misdiagnosis and unnecessary surgical resection.

Shock Study Finds E-Cigarettes May Raise Risk of Heart Failure

It's a myth that electronic cigarettes (e-cigarettes) are safer for your health than regular cigarettes.

SSRI Drugs Can Cause Chronic Fatigue Syndrome

Serotonin — also known as 5-hydroxytryptamine or 5-HT — is typically referred to as “the happiness hormone” and deﬁciency is thought to be the source of depression.

Plasma proteomics analysis of Chinese HIV-1 infected individuals focusing on the immune and inflammatory factors afford insight into the viral control mechanism

Background: Long-term non-progressors (LTNPs) with HIV infection can naturally control viral replication for up to a decade without antiretroviral therapy (ART), but the underlying mechanisms of this phenomenon remain elusive. Methods: To investigate the relevant immune and inflammatory factors associated with this natural control mechanism, we collected plasma samples from

Autoimmune uveitis attenuated in diabetic mice through imbalance of Th1/Th17 differentiation via suppression of AP-1 signaling pathway in Th cells

Inflammation is involved in the pathogenesis of diabetes, however the impact of diabetes on organ-specific autoimmune diseases remains unexplored.Experimental autoimmune uveoretinitis (EAU) is a widely accepted animal model of human endogenous uveitis. In this study, we investigated the effects of diabetic conditions on the development of EAU using a

Inhibition of interferon gamma impairs induction of experimental epidermolysis bullosa acquisita

Epidermolysis bullosa acquisita (EBA) is a muco-cutaneous autoimmune disease characterized and caused by autoantibodies targeting type VII collagen (COL7).

Anti-inflammatory and/or immunomodulatory activities of Uncaria tomentosa (cat's claw) extracts: a systematic review and meta-analysis of in vivo studies

Background: Uncaria tomentosa (Willd.ex Schult.) DC.(Rubiaceae), is traditionally used by Amazonian indigenous groups to treat inflammatory diseases.

Fascinating Research on Vitamin A From 1925

My colleague Pam Schoenfeld, MS, recently put me onto an eye-opening article on vitamin A.

Plasma fatty acids and attention deficit hyperactivity disorder: a Mendelian randomization investigation

Background: Attention deficit hyperactivity disorder (ADHD) is the most common neurodevelopmental disorder of childhood, and pathogenesis is not fully understood.

A streamlined workflow for a fast and cost-effective count of tyndallized probiotics using flow cytometry

The use of dead probiotics and their cellular metabolites seems to exhibit immunomodulatory and anti-inflammatory properties, providing protection against pathogens.

The treatment process of a giant phyllodes tumor of the breast: a case report and review of the literature

Giant phyllodes tumors are rare fibroepithelial tumors that are usually larger than 10 cm in diameter, have rapid tumor growth, and are easily recurrent.