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Biology

A collection of 1299 articles

PD-1 knockout on cytotoxic primary murine CD8+ T cells improves their motility in retrovirus infected mice

Cytotoxic T lymphocyte (CTL) motility is an important feature of effective CTL responses and is impaired when CTLs become exhausted, e.g.during chronic retroviral infections.

Immune niches for hair follicle development and homeostasis

The hair follicle is a dynamic mini-organ that has specialized cycles and architectures with diverse cell types to form hairs.

Association between gut microbiota and spinal stenosis: a two-sample mendelian randomization study

Introduction: Considerable evidence has unveiled a potential correlation between gut microbiota and spinal degenerative diseases.

4 Natural Ingredients to Care for Your Skin

As your body's largest organ, your skin provides an important barrier against pathogens, chemicals and injuries.

Gut microbiota is involved in male reproductive function: a review

Globally, ~8%−12% of couples confront infertility issues, male-related issues being accountable for 50%.

Rare microbial taxa as the major drivers of nutrient acquisition under moss biocrusts in karst area

Karst rocky desertification refers to the process of land degradation caused by various factors such as climate change and human activities including deforestation and agriculture on a fragile karst substrate. Nutrient limitation is common in karst areas. Moss crust grows widely in karst areas. The microorganisms associated with bryophytes are

Comprehensive genomic characterization and expression analysis of calreticulin gene family in tomato

Calreticulin (CRT) is a calcium-binding endoplasmic reticulum (ER) protein that has been identified for multiple cellular processes, including protein folding, regulation of gene expression, calcium (Ca2+) storage and signaling, regeneration, and stress responses. However, the lack of information about this protein family in tomato species highlights the importance of functional

Machine learning and weighted gene co-expression network analysis identify a three-gene signature to diagnose rheumatoid arthritis

Background: Rheumatoid arthritis (RA) is a systemic immune-related disease characterized by synovial inflammation and destruction of joint cartilage.

Pulmonary tuberculosis epidemiology and genetics in Kazakhstan

Background: Tuberculosis (TB) is a major public health emergency in many countries, including Kazakhstan.

The occurrence and development of induced pluripotent stem cells

The ectopic expression of four transcription factors, Oct3/4, Sox2, Klf4, and c-Myc (OSKM), known as “Yamanaka factors,” can reprogram or stimulate the production of induced pluripotent stem cells (iPSCs). Although OSKM is still the gold standard, there are multiple ways to reprogram cells into iPSCs. In recent years, significant

Have You Tried Curcumin for Indigestion?

Curcumin is the major biologically active polyphenolic compound of turmeric and the compound that gives the spice its yellow color.

Published Scientific Research on 5G, 4G Small Cells, Wireless Radiation and Health

Published peer reviewed science already indicates that the current wireless technologies of 2G, 3G and 4G – in use today with our cell phones, computers and wearable tech – creates (create) radiofrequency exposures which poses (pose) a serious health risk to humans, animals and the environment.

Reductive Stress — The Hidden Culprit of Chronic Disease

In this interview, Brad Marshall explains how reductive stress works, and why it's so bad for your health.

Can Onion Juice Reverse Thinning Hair and Slow Graying?

Onions are a veritable superfood, rich in antioxidants and organosulfur compounds that help ward off chronic disease.

The gut lactic acid bacteria metabolite, 10-oxo-cis-6,trans-11-octadecadienoic acid, suppresses inflammatory bowel disease in mice by modulating the NRF2 pathway and GPCR-signaling

Various gut bacteria, including Lactobacillus plantarum, possess several enzymes that produce hydroxy fatty acids (FAs), oxo FAs, conjugated FAs, and partially saturated FAs from polyunsaturated FAs as secondary metabolites. Among these derivatives, we identified 10-oxo-cis-6,trans-11-octadecadienoic acid (γKetoC), a γ-linolenic acid (GLA)-derived enon FA, as the most effective immunomodulator,