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Dan Simmer

PD-1 knockout on cytotoxic primary murine CD8+ T cells improves their motility in retrovirus infected mice

Cytotoxic T lymphocyte (CTL) motility is an important feature of effective CTL responses and is impaired when CTLs become exhausted, e.g.during chronic retroviral infections.

Unraveling the core symptoms of mental health in senior grade three students- a network analysis

Background: Adolescence is not only an important transitional period of many developmental challenges, but also a high risk period for mental health problems.

Diagnostic value of retinol-binding protein 4 in diabetic nephropathy: a systematic review and meta-analysis

Objective: Diabetic nephropathy (DN) is a major microvascular complication of diabetes and the leading cause of end-stage renal disease.Early detection and prevention of DN are important.

4 Natural Ingredients to Care for Your Skin

As your body's largest organ, your skin provides an important barrier against pathogens, chemicals and injuries.

Machine learning and weighted gene co-expression network analysis identify a three-gene signature to diagnose rheumatoid arthritis

Background: Rheumatoid arthritis (RA) is a systemic immune-related disease characterized by synovial inflammation and destruction of joint cartilage.

Have You Tried Curcumin for Indigestion?

Curcumin is the major biologically active polyphenolic compound of turmeric and the compound that gives the spice its yellow color.

Reductive Stress — The Hidden Culprit of Chronic Disease

In this interview, Brad Marshall explains how reductive stress works, and why it's so bad for your health.

A Guide to Spring Cleaning

While this spring is different from the ones we’ve experienced in the past, the rituals of cleansing can still happen from the comforts of your home.

Alzheimer's Is Now a Leading Cause of Death

Alzheimer's disease, a severe form of dementia, affected an estimated 6.7 million Americans in 2023.

Osteolytic lesions as a presenting sign of acute myeloid leukemia: a case report

Osteolytic lesions are infrequently observed in adult patients with acute myeloid leukemia (AML).

How Mandarin-English Bilinguals Interpret qián/forward：Impact of language proficiencies on retrieval of temporal concepts

Mandarin qián and English forward are semantically equivalent in the domain of Space, but could be semantically opposite in the domain of Time.

Fever in childbirth: A mini-review of epidural-related maternal fever

Fever during childbirth, which is often observed in clinical settings, is characterized by a temperature of 38°C or higher, and can occur due to infectious and non-infectious causes.

Micronutrients and Exercise Ameliorate Aging

The video above features a lecture by Rhonda Patrick Ph.D., a cell biologist and cofounder of FoundMyFitness, at the American Academy of Anti-Aging Medicine Longevity Fest in 2023.

Ventriculitis due to multidrug-resistant gram-negative bacilli associated with external ventricular drain: evolution, treatment, and outcomes

Introduction: Nosocomial infectious ventriculitis caused by multidrug-resistant (MDR) Gram-negative bacilli associated with external ventricular drainage (EVD) placement poses a significant mortality burden and hospital costs. Objectives: This study aims to analyze the characteristics, ventriculitis evolution, treatment, and outcomes of patients with ventriculitis due to MDR Gram-negative bacilli associated with EVD

Mobilizing endogenous neuroprotection: the mechanism of the protective effect of acupuncture on the brain after stroke

Given its high morbidity, disability, and mortality rates, ischemic stroke (IS) is a severe disease posing a substantial public health threat.