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John Foo

Plasma proteomics analysis of Chinese HIV-1 infected individuals focusing on the immune and inflammatory factors afford insight into the viral control mechanism

Background: Long-term non-progressors (LTNPs) with HIV infection can naturally control viral replication for up to a decade without antiretroviral therapy (ART), but the underlying mechanisms of this phenomenon remain elusive. Methods: To investigate the relevant immune and inflammatory factors associated with this natural control mechanism, we collected plasma samples from

Characterizing health-related quality of life and identifying disease predictors among patients suspected of having long COVID: an analysis of COMET-ICE clinical trial data

Introduction: Long COVID affects health-related quality of life (HRQoL).

Actions Speak Louder than Words; Pediatricians, gynecologists, nurses, and other mothers' perspectives on the human papillomavirus vaccine: an Istanbul multicenter study

Gynecologists and pediatricians have an essential duty to prevent cervical cancer.

Autoimmune uveitis attenuated in diabetic mice through imbalance of Th1/Th17 differentiation via suppression of AP-1 signaling pathway in Th cells

Inflammation is involved in the pathogenesis of diabetes, however the impact of diabetes on organ-specific autoimmune diseases remains unexplored.Experimental autoimmune uveoretinitis (EAU) is a widely accepted animal model of human endogenous uveitis. In this study, we investigated the effects of diabetic conditions on the development of EAU using a

Fascinating Research on Vitamin A From 1925

My colleague Pam Schoenfeld, MS, recently put me onto an eye-opening article on vitamin A.

Only YOU can stop euthanasia

Plasma fatty acids and attention deficit hyperactivity disorder: a Mendelian randomization investigation

Background: Attention deficit hyperactivity disorder (ADHD) is the most common neurodevelopmental disorder of childhood, and pathogenesis is not fully understood.

A nomogram for predicting cerebral white matter lesions in elderly men

Objective: This study aimed to develop a nomogram tool to predict cerebral white matter lesions (WMLs) in elderly men.

The research progress of perioperative non-pharmacological interventions on postoperative cognitive dysfunction: a narrative review

Postoperative cognitive dysfunction (POCD) is a common neurological complication in elderly patients after surgery and general anesthesia.

Genomic prediction for sugarcane diseases including hybrid Bayesian-machine learning approaches

Sugarcane smut and Pachymetra root rots are two serious diseases of sugarcane, with susceptible infected crops losing over 30% of yield.

Long-Term Oral Administration of Huaier Granules Improves Survival Outcomes in Hepatocellular Carcinoma Patients Within Milan Criteria following Microwave Ablation: A Propensity Score Matching and Stabilized Inverse Probability Weighting Analysis

Objective: This study aimed to elucidate the therapeutic effects of Huaier granules on hepatocellular carcinoma (HCC) within the Milan criteria in patients who underwent microwave ablation (MWA). Materials and Methods: A total of 228 patients were included, with 97 in the Huaier group and 131 in the control group. We

What We Don’t Seem to Care About

When I say “we” in the title of this article, I don’t mean us shrews.

Epigenetically active chromatin in neonatal iWAT reveals GABPα as a potential regulator of beige adipogenesis

Background: Thermogenic beige adipocytes, which dissipate energy as heat, are found in neonates and adults.

Coal mining environment causes adverse effects on workers

Background: The objective of this study is to study the adverse effects of coal mining environment on workers to discover early effective biomarkers.