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Clara Steitz

Preclinical characterization of a novel investigational monoclonal antibody CM313 with potent CD38-positive cell killing activity

Introduction: CM313 is currently under clinical investigation for treatments of multiple myeloma, systemic lupus erythematosus, and immune thrombocytopenia.

Advances in Determining the Gross Tumor Target Volume for Radiotherapy of Brain Metastases

Brain metastases (BMs) are the most prevalent intracranial malignant tumors in adults, and are the leading cause of mortality attributed to malignant brain diseases.

SSRI Drugs Can Cause Chronic Fatigue Syndrome

Serotonin — also known as 5-hydroxytryptamine or 5-HT — is typically referred to as “the happiness hormone” and deﬁciency is thought to be the source of depression.

Enhancing immigrant families' mental health through promotion of structural and community-based support

Immigrant communities in the US are diverse and have many assets.Yet, they often experience stressors that can undermine the mental health of residents.

Inhibition of interferon gamma impairs induction of experimental epidermolysis bullosa acquisita

Epidermolysis bullosa acquisita (EBA) is a muco-cutaneous autoimmune disease characterized and caused by autoantibodies targeting type VII collagen (COL7).

Unraveling genetic causality between metformin and myocardial infarction on the basis of Mendelian randomization

Background: In recent years, several studies have explored the effect of metformin on myocardial infarction (MI), but whether metformin has an improvement effect in patients with MI is controversial.

Diet Soda Linked to Serious Heart Condition Risk

Research published in the American Heart Association journal Circulation: Arrhythmia and Electrophysiology found an association between drinking sweetened beverages and atrial ﬁbrillation.

Physical activity, musculoskeletal disorders, burnout, and work engagement: a cross-sectional study on Italian white-collar employees

Introduction: Both mental and physical health of office workers had a positive relationship with their work engagement, with the latter relationship being driven by the association of a healthy diet and physical activity (PA). This observational study aimed to investigate the associations between PA levels, musculoskeletal disorders (MSDs), burnout, and

Salidroside alleviates cholestasis-induced liver fibrosis by inhibiting hepatic stellate cells via activation of the PI3K/AKT/GSK-3β signaling pathway and regulating intestinal flora distribution

Salidroside (SAL), a phenylpropanoid bioactive compound, has various pharmacological properties, including antioxidant, anti-inflammatory, and hepatoprotective effects.

Identification of PANoptosis-related subtypes, construction of a prognosis signature, and tumor microenvironment landscape of hepatocellular carcinoma using bioinformatic analysis and experimental verification

Background: Hepatocellular carcinoma (HCC) is one of the most lethal malignancies worldwide.

An exploration on the machine-learning-based stroke prediction model

With the rapid development of artificial intelligence technology, machine learning algorithms have been widely applied at various stages of stroke diagnosis, treatment, and prognosis, demonstrating significant potential. A correlation between stroke and cytokine levels in the human body has recently been reported. Our study aimed to establish machine-learning models based

Peter Gøtzsche: Scientists must stand up to governments who act against the evidence

Cochrane Collaboration co-founder Peter Gøtzsche has written an article that reads as an open letter to scientists the world over. “Looking back, it seems appropriate to abbreviate the covid-19 pandemic as the covid-19 panic, or to call it the pandemic of censorship and poor science,” he writes. Science and free

Don’t Underestimate the Power of a Good Walk

Daily walking is one of the most effective ways to stay ﬁt and active, yet many overlook it in favor of ﬂashier forms of exercise.

Unmasking the Hidden Dangers: How mRNA C-19 Vaccines Can Compromise Your Immune System & Essentially Cause “VAIDS”

The COVID-19 pandemic led to an unprecedented global effort to develop and distribute vaccines.

Rapid Identification of Pediatric Brain Tumors with Differential Mobility Spectrometry

Brain tumors are a major source of disease burden in pediatric population, with the most common tumor types being pilocytic astrocytoma, ependymoma and medulloblastoma.