Autoimmune uveitis attenuated in diabetic mice through imbalance of Th1/Th17 differentiation via suppression of AP-1 signaling pathway in Th cells

Inflammation is involved in the pathogenesis of diabetes, however the impact of diabetes on organ-specific autoimmune diseases remains unexplored.Experimental autoimmune uveoretinitis (EAU) is a widely accepted animal model of human endogenous uveitis. In this study, we investigated the effects of diabetic conditions on the development of EAU using a

Epidemiology and Antimicrobial Resistance of Mycobacterium spp. in the United Arab Emirates: A retrospective analysis of twelve years of National AMR Surveillance Data

The Eastern Mediterranean Regional Office (EMRO) region accounts for almost 8% of all global Mycobacterium tuberculosis (TB) cases, with TB incidence rates ranging from 1 per 100,000 per year in the United Arab Emirates (UAE) to 204 per 100,000 in Djibouti. The national surveillance data from the EMRO/

Effect of needle-free injection on psychological insulin resistance and insulin dosage in patients with type 2 diabetes

Background and Objective: Psychological insulin resistance (PIR), which refers to the reluctance of diabetic patients to use insulin, is a frequently encountered clinical issue.

Enhancing immigrant families' mental health through promotion of structural and community-based support

Immigrant communities in the US are diverse and have many assets.Yet, they often experience stressors that can undermine the mental health of residents.

Inhibition of interferon gamma impairs induction of experimental epidermolysis bullosa acquisita

Epidermolysis bullosa acquisita (EBA) is a muco-cutaneous autoimmune disease characterized and caused by autoantibodies targeting type VII collagen (COL7).

Anti-inflammatory and/or immunomodulatory activities of Uncaria tomentosa (cat's claw) extracts: a systematic review and meta-analysis of in vivo studies

Background: Uncaria tomentosa (Willd.ex Schult.) DC.(Rubiaceae), is traditionally used by Amazonian indigenous groups to treat inflammatory diseases.

What Is Aloe Vera Good For?

Editor's Note: This article is a reprint.

Fascinating Research on Vitamin A From 1925

My colleague Pam Schoenfeld, MS, recently put me onto an eye-opening article on vitamin A.

Only YOU can stop euthanasia

Recently, Dr.

Unraveling genetic causality between metformin and myocardial infarction on the basis of Mendelian randomization

Background: In recent years, several studies have explored the effect of metformin on myocardial infarction (MI), but whether metformin has an improvement effect in patients with MI is controversial.

Plasma fatty acids and attention deficit hyperactivity disorder: a Mendelian randomization investigation

Background: Attention deficit hyperactivity disorder (ADHD) is the most common neurodevelopmental disorder of childhood, and pathogenesis is not fully understood.

A streamlined workflow for a fast and cost-effective count of tyndallized probiotics using flow cytometry

The use of dead probiotics and their cellular metabolites seems to exhibit immunomodulatory and anti-inflammatory properties, providing protection against pathogens.

A nomogram for predicting cerebral white matter lesions in elderly men

Objective: This study aimed to develop a nomogram tool to predict cerebral white matter lesions (WMLs) in elderly men.

The treatment process of a giant phyllodes tumor of the breast: a case report and review of the literature

Giant phyllodes tumors are rare fibroepithelial tumors that are usually larger than 10 cm in diameter, have rapid tumor growth, and are easily recurrent.

Does the level of burnout differ between occupational groups in Lithuania?

Background: The strain on workers of the healthcare system and education sector increased psychological distress and burnout.