Ventriculitis due to multidrug-resistant gram-negative bacilli associated with external ventricular drain: evolution, treatment, and outcomes

Introduction: Nosocomial infectious ventriculitis caused by multidrug-resistant (MDR) Gram-negative bacilli associated with external ventricular drainage (EVD) placement poses a significant mortality burden and hospital costs. Objectives: This study aims to analyze the characteristics, ventriculitis evolution, treatment, and outcomes of patients with ventriculitis due to MDR Gram-negative bacilli associated with EVD

Mobilizing endogenous neuroprotection: the mechanism of the protective effect of acupuncture on the brain after stroke

Given its high morbidity, disability, and mortality rates, ischemic stroke (IS) is a severe disease posing a substantial public health threat.

A Multimodal Exertional Test for concussion: a pilot study in healthy athletes

Introduction: Exertional tests have become a promising tool to assist clinicians in the management of concussions, however require expensive equipment, extensive spaces, and specialized clinician expertise. As such, we developed a test with minimal resource requirements encompassing key elements of sport and physical activity. The purpose of this study was

Genetics of Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome: advancements and implications

Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome is a congenital anomaly characterized by agenesis/aplasia of the uterus and upper part of the vagina in females with normal external genitalia and a normal female karyotype (46,XX). Patients typically present during adolescence with complaints of primary amenorrhea where the diagnosis is established with

Cognitive training interventions for substance use disorders: what they really offer?

Cognitive training (CT) has emerged as a potential therapeutic approach for substance use disorders (SUD), aiming to restore cognitive impairments and potentially improve treatment outcomes.

Postoperative cognitive dysfunction: spotlight on light, circadian rhythms, and sleep

Postoperative cognitive dysfunction (POCD) is a neurological disorder characterized by the emergence of cognitive impairment after surgery.

The Story of Rachel Carson: How Her Love for Nature Changed the Way Humans View the Environment

One of the most celebrated American writers of her time, Rachel Carson, achieved the impossible: convincing a society intent on mastering and controlling nature that we, as humans, must view ourselves as being part of nature rather than separate from it.

Average Person Asleep by 10 but Still Wakes Up Tired

Getting to bed too late is often blamed for feeling groggy the next morning.

Hydrosol Misters: Renew Stagnant Energy

The Summer of 2023 is a planetary headline for record temperatures of extreme heat.Perhaps, this is a well-deserved justification for the growing interest in plant-based topical misters and hydrosols.

The Rockefellers’ long-standing battle with the climate change cult is not what it seems

Almost 15 years ago Jacob Nordangård began researching the politics behind climate change.

Gen Z: the ‘No Nic’ generation

The JAMA Network shows that between 1999 and 2017, Nicotine usage amongst high-school-aged youths decreased rapidly, as our knowledge of the long-term impacts of smoking grew, and fewer and fewer young people decided to take it up. And then, suddenly, between 2017 and 2019, nicotine use was on the rise

Comprehensive molecular profiling identifies actionable biomarkers for patients from Thailand and the United Arab Emirates with advanced malignancies

Background: Comprehensive molecular profiling of tissue samples that can help guide therapy management is not widely available across the globe.

The immunomodulatory mechanism of acupuncture treatment for ischemic stroke: research progress, prospects, and future direction

Ischemic stroke (IS) is one of the leading causes of death and disability.Complicated mechanisms are involved in the pathogenesis of IS.Immunomodulatory mechanisms are crucial to IS.

The digestion and dietary carbohydrate pathway contains 100% gene mutations enrichment among 117 patients with major depressive disorder

Introduction: Major depressive disorder (MDD) is partially inheritable while its mechanism is still uncertain.

Risk prediction model based on machine learning for predicting miscarriage among pregnant patients with immune abnormalities

Introduction: It is known that patients with immune-abnormal co-pregnancies are at a higher risk of adverse pregnancy outcomes.