Spinocerebellar Ataxias: from Pathogenesis to Recent Therapeutic Advances
Spinocerebellar ataxia is a phenotypically and genetically heterogeneous group of autosomal dominant-inherited degenerative disorders.
Dan Simmer
Beyond Impossible — The Truth Behind the Fake Meat Industry
A 2024 systematic review of the literature confirmed what multiple studies have shown — the higher your intake of ultraprocessed food, the higher your risk of adverse health outcomes.
Changes in Soil Organic Carbon Components and Microbial Community Following Spent Mushroom Substrate Application
While spent mushroom substrate (SMS) has shown promise in increasing soil organic carbon (SOC) and improving soil quality, research on the interplay between SOC components and microbial community following the application of diverse SMS types remains scant. A laboratory soil incubation experiment was conducted with application of two types of
Noninvasive Assessment of Ki-67 Labeling Index in Glioma Patients based on Multi-parameters derived from Advanced MR Imaging
Purpose: To investigate the predictive value of multi-parameters derived from advanced MR imaging for Ki-67 labeling index (LI) in glioma patients.Materials and Methods: One hundred and nine patients with histologically confirmed gliomas were evaluated retrospectively.
These patients underwent advanced MR imaging, including dynamic susceptibility-weighted contrast enhanced MR imaging (DSC)
Natural Therapies for Cystic Fibrosis
Cystic fibrosis (CF) is a progressive and terminal genetic disease that causes an overproduction and buildup of thick, sticky mucus in the lungs and other organs that lead to chronic inflammation and, eventually, a deterioration of lung function. The disease requires daily breathing treatment for up to five hours a
Ex vivo expansion in a clinical grade medium, containing growth factors from human platelets, enhances migration capacity of adipose stem cells
Adipose tissue mesenchymal stem/stromal cells (ASC) can be used as advanced therapy medicinal product in regenerative and cancer medicine.
Food Additive in Pizza, Pancakes Linked to Lower Sperm Counts
On March 7, 2024, Dr.
MRI-Based Intratumoral and Peritumoral Radiomics for Preoperative Prediction of Glioma Grade: a multicenter study
Background: Accurate preoperative prediction of glioma is crucial for developing individualized treatment decisions and assessing prognosis.
CBDCs: “Financial inclusion” means the inclusion of all transactions not people
To try to make central bank digital currencies sound benign, proponents repeatedly use the word “financial inclusion.” They are trying to convince us that the world needs CBDCs so that those who are “unbanked” can participate in the digital economy without requiring a bank account.
This is, of course, absurd,
Macrophage polarization in rheumatoid arthritis: signaling pathways, metabolic reprogramming, and crosstalk with synovial fibroblasts
Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by persistent synovial inflammation and progressive joint destruction.
Exploration of the Mechanism of Traditional Chinese Medicine for Anxiety and Depression in Patients with Diarrheal Irritable Bowel Syndrome Based on Network Pharmacology and Meta-analysis
The efficacy of Chinese herbal medicine (CHM) in managing irritable bowel syndrome with diarrhea (IBS-D) accompanied by anxiety and depression remains uncertain.
Exploration of the Mechanism of Traditional Chinese Medicine for Anxiety and Depression in Patients with Diarrheal Irritable Bowel Syndrome Based on Network Pharmacology and Meta-analysis
The efficacy of Chinese herbal medicine (CHM) in managing irritable bowel syndrome with diarrhea (IBS-D) accompanied by anxiety and depression remains uncertain.
Association between human blood metabolites and cerebral cortex architecture: evidence from a Mendelian randomization study
Background: Dysregulation of circulating metabolites may affect brain function and cognition, associated with alterations in the cerebral cortex architecture.However, the exact cause remains unclear.
Mendelian randomization and single-cell expression analyses identify the causal relationship between depression and chronic rhinosinusitis
The causative relationship between chronic rhinosinusitis (CRS) and depression remains unclear.
Deciphering Glycosylation-Driven Prognostic Insights and therapeutic Prospects in Glioblastoma through a Comprehensive Regulatory Model
The oncogenesis and development of glioblastoma multiforme have been linked to glycosylation modifications, which are common post-translational protein modifications.
